Substrate: Bifunctional polynucleotide phosphatase/kinase (ATP binding)
Seq-ID: Q96T60 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-51173   XRCC4_HUMAN
MINT-61828   SMAD5_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
nucleotide kinase activity,
polynucleotide 3`-phosphatase activity,
endonuclease activity,
double-stranded DNA binding,
ATP binding,
damaged DNA binding,
ATP-dependent polydeoxyribonucleotide 5`-hydroxyl-kinase activity,
protein binding		 nucleolus response to oxidative stress,
DNA damage response, detection of DNA damage,
nucleotide-excision repair, DNA damage removal,
response to radiation,
DNA-dependent DNA replication
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 114 LRWEETRTPESQPDTPPGTPL - 17525332
HTP
0.11
 - -
0.89
 - medium
T 118 ETRTPESQPDTPPGTPLVSQD - 17081983
HTP
0.49
 - -
0.93
 - medium
T 118 ETRTPESQPDTPPGTPLVSQD - 17525332
HTP
0.49
 - -
0.93
 - medium
T 118 ETRTPESQPDTPPGTPLVSQD - 18669648
HTP
0.49
 - -
0.93
 - medium
T 122 PESQPDTPPGTPLVSQDEKRD - 17081983
HTP
0.11
 - -
0.92
 - medium
T 122 PESQPDTPPGTPLVSQDEKRD - 18669648
HTP
0.11
 - -
0.92
 - medium
S 126 PDTPPGTPLVSQDEKRDAELP - 17525332
HTP
0.43
 - -
0.86
 - medium

Substrate: Bifunctional polynucleotide phosphatase/kinase (ATP binding)
Seq-ID: Q9JLV6 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
polynucleotide 3`-phosphatase activity,
ATP binding,
ATP-dependent polydeoxyribonucleotide 5`-hydroxyl-kinase activity		 DNA repair
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 114 LRWEELSTSGSQPDAPPDTPG - 17525332
HTP
0.12
 - -
0.84
 --
T 122 SGSQPDAPPDTPGDPEEGEDT - 17525332
HTP
0.13
 - -
0.98
 --

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